TGF α (34-43) (rat),CAS:97474-88-9

The fragment CHSGYVGVRC comprises the third disulfide loop of rat TGF α. Antibodies elicited against the synthetic decapeptide crossreacted with native TGF α but not EGF. The peptide competed with EGF for binding to its receptors and was found to be an antagonist of EGF-induced mitogenesis. More recent results indicate that administration of TGF α (34-43) inhibits the development of gastric cancers induced by N-methyl-N-nitro-N-nitrosoguanidine.

msds of TGF α (34-43) (rat)